会议专题

Determining Thermal Stability of Antibodies with a Nano DSC

Antibodies or immunoglobulins are a specific type ofglycoprotein.There are billions of forms, each with a different primary sequence and antigen binding site (1).Mammals have five classes of antibodies, IgA, IgD, IgE, IgM, and IgG; the major class of antibodies in the blood is IgG.A typical antibody structure is Y-shaped.The tail is referred to as the Fc (fragment crystallizable) region and the two arms, the Fab (fragment, antigen binding) regions.Each Fab region, the red and blue portions paired with the green and yellow regions in the structure below, contains the highly variable regions of the molecule and an antigen binding site (1).

Colette F.Quinn Neil A.Demarse

TA Instruments, 890 West 410 North, Lindon, UT 84042, USA

国内会议

2015年生物技术药物理化特性分析与质量研究技术研讨会

北京

英文

152-156

2015-07-17(万方平台首次上网日期,不代表论文的发表时间)