Enthalpy Screening by Isothermal Titration Calorimetry

摘要：

There are situations in which it is necessary to measure the binding enthalpy of a relatively large number of compounds for which binding affinities or IC50”s have already been estimated using other approaches.In drug discovery for example, high throughput screening (HTS) is usually the first step in the identification of potential lead compounds.

作者: Patrick C.Ross Ernesto Freire

作者单位: Department of Biology, Johns Hopkins University

会议类型: 国内会议

会议名称: 2015年生物技术药物理化特性分析与质量研究技术研讨会

会议地点: 北京

会议语种:英文

页码: 164-168

在线出版日期: 2015-07-17（万方平台首次上网日期，不代表论文的发表时间）