Preventive intracoronary administration of anisodamine improves myocardial perfusion in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention
Background To evaluate the effects of preventive administration of intracoronary anisodamine on myocardial perfusion in terms of slow/no reflow during primary percutaneous coronary intervention (PCI).Methods From January 2011 to January 2012, a total of 186 patients undergoing primary PCI within 12 hours from the onset of STEMI were enrolled.Eligible patients were randomly assigned to receive anisodamine (ANI, n=95) or placebo(CON, n=91).All patients in the two groups were pretreated with intravenous tirofiban in the emergency room immediately after diagnosis was confirmed.Intracoronary anisodamine was administered immediately prior to balloon inflation and at short intervals during the procedure thereafter, while patients in CON group received intracoronary administration of 0.9％ sodium chloride with the same volume as ANI group in the same way.Angiographic characteristics were compared.
FU Xiang-hua WANG Xue-chao WANG Yan-bo GU Xin-shun GENG Wei LI Wei HAO Guo-zhen JIANG Yun-fa
The Second Hospital of Hebei Medical University,Shijiazhuang,China
国内会议
北京
英文
1-1
2013-03-20（万方平台首次上网日期，不代表论文的发表时间）