Extracorporeal cardiac shock wave therapy (CSWT) for treatment of coronary artery disease
Background Cardiac shock wave therapy (CSWT) is a novel, noninvasive intervention that propagates though water as a spike ＜ 1 μs in duration with an amplitude up to 100 MPa, that is followed by a lower amplitude tensile portion lasting several microseconds.Early studies with animal models of angina pectoris and AMI indicated that CSWT at approximately 10％ of the energy used for lithotripsy could improve lett ventricular wall motion, LVEF, LV end-diastolic volume, and regional blood flow and number of capillaries in the border zone of AMI.However, the exact mechanism by which shock waves promote neovascularization and improvement of cardiac function has not been determined.To prove up the angiogenetic mechanism and effect of CSWT in vivo and in vitro experiments, also to evaluate the feasibility and efficiency of CSWT for treatment of CAD and to establish the inclusion and exclusion criteria and summarize themethodological outlines of CSWT in China.
GUO Tao WANG Yu TAO Si-ming SUN Shuai CAI Hong-yan YANG Ping PENG Yun-zhu HUA Bao-tong YANG Wen-hui
The 1st Hospital of Kunming Medical University
国内会议
北京
英文
45-46
2013-03-20（万方平台首次上网日期，不代表论文的发表时间）