Rosuvastatin inhibits stent thrombosis by inducing Krüppel-like transcription factor 2

摘要：

Background Krüppel-like transcription factor 2 (KLF2) has been identified as a key regulator of endothelial antithrombotic function.KLF2 was strongly implicated to be a novel nuclear mediator of statin effects in association between coronary risk factors and atherosclerotic disease burden measured by intravascular ultrasound endothelial cells.We hypothesized that rosuvastatin might induce the expression and activity of KLF2, thereby counteracting coronary endothelial dysfunction induced by DESs.

作者: MA Qian YU Miao YANG Shi-wei JIA De-an ZHOU Yue-jie

作者单位: Capital Medical University Affiliated Beiing Anzhen Hospital and Beijing Institute of Heart,Lung and Blood Vessel Diseases,Beijing,China

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 66-67

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）