Relationship between aspirin and clopidogrel resistance in acute coronary syndrome

摘要：

Background We have prospectively investigated the association between aspirin and clopidogrel low responsiveness.Methods 635 Non ST Elevation Acute Coronary Syndrome (NSTE ACS) patients were included and received loading doses of 300 mg aspirin and 600 mg clopidogrel.We analyzed post-treatment maximal intensity of arachidonic acid and ADP-induced platelet aggregation (AA-Ag and ADP-Ag) and Platelet Reactivity Index of VAsodilator-Stimulated Phosphoprotein (PRI VASP).Aspirin and clopidogrel low responsiveness were defined respectively by AA-Ag ＞30％and ADP-Ag ＞70％.

作者: SHEN Hua ZHOU Yujie LIU Yuyang WANG Zhijian YANG Shiwei HAN Hongya GAO Fei

作者单位: Beijing Anzhen Hospital Affiliated to Capital Medical University,Beijing,China

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 77-78

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）