Effect of probucol before percutatneous coronary intervention on periprocedural myocardial infarction

摘要：

Background Periprocedural myocardial infarction (MI) is an independent predictor of adverse clinical outcomes.Oxidant injury is one of the most important mechanisms of periprocedural MI.Methods In this prospective, single-center, randomized study, 280 patients were randomized into two groups: the probucol group (n=143), who received probucol 250 mg bid 3 days before procedure, versus control group (n=137),which received routine treatment.The primary endpoint was the incidence ofperiprocedural MI, defined as the elevationof elevation of cardiac enzymes (CK-MB or cTNI) more than three times the 99th centile upper reference limit within 24hours after the procedure.

作者: YU Miao ZHOU Yu-jie

作者单位: Bering Institute of Heart Lung and Blood Vessel Diseases,Beijing 100029,China

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 82-83

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）