SIRT1 significantly influences old sourced MSCs aging and proliferation

摘要：

Background There is an age-related decline in mesenchymal stem cells (MSCs) functions and old age has a negative effect on MSCs aging and proliferation.The study aims to investigate the role of SIRT 1, a NAD+dependent histone deacetylase, in old sourced MSCs senescence and proliferation; we examined the effects of Sirtl manipulationin Old sourced MSCs.

作者: CHEN Hui-qiang LIU Xian-bao HU Xin-yang WANG Jian-an

作者单位: Cardiovascular Key Lab of Zhejiang Province,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 116-116

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）