Transgenic zebrafish model of cardiac hypertrophy induced by an AMP-activated protein kinase loss-of-function mutation responsible for PRKAG2 cardiac syndrome

摘要：

Background We identified a gene (PRKAG2) that encodes the γ-2 regulatory subunit of AMP-activated protein kinase(AMPK) with a novel mutation (Gly100Ser) responsible for PRKAG2 cardiac syndrome (PCS).The human phenotype consists of ventricular preexcitation, conduction abnormalities, and cardiac hypertrophy.

作者: ZHANG Bi-li QIN Yong-wen ZHENG Xing ZHAO Xian-xian YE Zhong XU Rong-liang MA Li-ping ZHANG Jian-liang CAO Jiang WU Hong HU Jian-qiang CHEN Shao-ping

作者单位: Department of Cardiology,Changhai Hospital Second Military Medical University

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 117-117

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）