Kruppel-like factor 4 promotes differentiation of endothelial progenitor cells into endothelial cells by up-regulating endothelial nitric oxide synthase

摘要：

Background The differentiated function of endothelial progenitor cells (EPCs) may play an pivotal roles in endothelial repair and reendothelialization replacement of postinjury endothelium, However, the mechanism of differentiation of EPCs remains unclear.One of zinc finger transcription factors family members, KLF4, was involved in the regulation of numerous biological processes including proliferation, differentiation, development, and apoptosis.This present study was designed to investigate whether transcription factors, Krüppel-like factor 4 (KLF4) is involved in the differentiation of EPCs derived from bone marrow (BM-EPCs) into endothelial cells (ECs).

作者: DONG Hong-mei HUANG Lan DENG Meng-yang SONG Ming-bao CHEN Jian-fei WANG Qiang

作者单位: Institute of Cardiovascular Disease,Xinqiao Hospital,Chongqing,China

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 118-118

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）