Effects of hydrogen sulfide on proliferation of bone marrow derived endothelial progenitor cells in mice
Background Hydrogen sulfide (H2S) is found to be the third endogenous gaseous transmitter and plays an important role in many systems of organism.In cardiovascular system, H2S is produced endogenously by cystathionine gamma-lyase (CSE).The CSE/H2S system executes the physiological function of vasorelaxation, inhibition of vascular remodeling and cardioprotection.It is also concerned with variety of cardiovascular diseases such as hypertension and pulmonary hypertension.These results suggest that H2S may be a novel cardiovascular functional regulator.And, at another hand, EPCs incorporate into the process of injured carotid reendothelialization.EPCs transplantation induces an increase in the circulating EPCs, accelerates the process of endothelial repairmen and reduces neointima formation.To study whether hydrogen sulfide has effects on endothelial progenitor cells (EPCs).
LI Wei LI Ai-min WANG Hong ZHU Jin-kun QIN Zhe-xue HUANG Lan
Institute of Cardiovascular Disease,Xinqiao Hospital
国内会议
北京
英文
119-119
2013-03-20（万方平台首次上网日期，不代表论文的发表时间）