Association between polymorphism in the chemokine CCL21 gene rs10972201 and coronary artery disease in Chinese Han population

摘要：

Background Atherosclerosis is an inflammatory disease characterized by the formation of atherosclerotic plaques.Homeostatic chemokine CCL21 was up-regulated within the atherosclerotic lesions, which could potentially contribute to atherogenesis and plaque destabilization with subsequent thrombus formation and development of acute ischemic events.Although CCL21 expression may be genetically determined, the relationship between CCL21 polymorphisms and the risk of coronary artery disease (CAD) is unclear.The aim of this study was to investigate the relationship between the polymorphism of CCL21 rs10972201 and the CAD in a Chinese Han population.

作者: CAI Wen-zhi ZHANG Xiao-lin FENG Xue-yao BAI Jing LIU Teng-fei HAN Ya-ling

作者单位: Department of Cardiology,Institute of Cardiovascular Research of People”s Liberation Army,Shenyang Northern Hospital Shenyang,Liaoning 110840,China

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 120-120

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）