Relationship between paraoxonase 1 (PON1) gene polymorphisms, haplotypes, concentration, activity and immunohistochemical analysis with coronary artery disease risk in Chinese Han population

摘要：

Background Paraoxonase l (PON1) is an high-density lipoprotein (HDL)-associated enzyme capable of inhibiting the progression of atherosclerosis, thus preventing the development of coronary artery disease (CAD).The polymorphisms of PON1 gene are known to affect the PON1 concentration and activity, thereby affect the CAD risk.As to its crucial role in preventing of CAD, we determined PON1 polyrnorphisms and haplotypes, concentration and activity, in addition to the immunohistochemical analysis of PON1 in this population and correlated them with the risk of CAD.

作者: LIU Teng-fei ZHANG Xiao-lin CAI Wen-zhi YAN Cheng-hui ZHANG Jian SUN Ying HAN Ya-ling

作者单位: Department of Cardiology,Institute of Cardiovascular Research of People”s Liberation Army,Shenyang Northern Hospital,Shenyang,Liaoning 110840,China

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 121-121

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）