Protective effect of trimetazidine on myocardial injury and recurrent angina after percutaneous coronary intervention
Objective To explore the effect of trimetazidine (TMZ) on the myocardial injury related to percutaneous coronary intervention (PCI) and left heart function after PCI.Methods 132 patients with unstable angina pectoris admitted for elective PCI were randomly assigned to 2 groups to receive or not an acute load dose of 60 mg of TMZ prior to the intervention and routine dose of 20 mg Tid after it.The frequency and the increase in the level of cTnI after successful PCI were measured before and 16-18 hours after PCI.Heart function evaluated by echocardiography and major adverse cardiac events (MACE, including death, re-infarction and target vessel revascularization) at 12 months after the procedure were also compared.
XU Xiao-han ZHOU Yu-jie ZHANG Wei-jun ZHOU Zhi-ming MA Han-ying HU Bin KANG Yun-peng LUO Fang-fang
Beijing Anzhen Hospital Affiliated to Capital Medical University Beijing Institute of Heart and Blood Vessel Diseases,Beijing 100029,China
国内会议
北京
英文
206-206
2013-03-20（万方平台首次上网日期，不代表论文的发表时间）