Expression and significane of transcription factors KLF4 in differentiated endothelial progenitor cells
Background The vascular endothelium is a vital organ whose health is essential to normal vascular physiology and whose dysfunction can be a critical factor in the pathogenesis of vascular disease.Postnatal bone marrow contains a subtype of unique progenitor cells that have the capacity to differentiate into functional endothelial cells.Hence, these cells have been termed endothelial progenitor cells (EPCs).KLF4 has recently been independently implicated byindependent groups as being important in maintaining pluripotent state of stem cells.This present study was designed to investigate the expression and significane of transcription factors KLF4 in differentiated endothelial progenitor cells.
DONG Hong-mei HUANG Lan DENG Meng-yang SONG Ming-bao
Institute of Cardiovascular Disease,Xinqiao Hospital
国内会议
北京
英文
255-256
2013-03-20(万方平台首次上网日期,不代表论文的发表时间)