Simvastatin decreases stent-induced in-stent restenosis rate via down-regulating the expression of PCNA and up-regulating that of p27kip1

摘要：

Background The inhibition of the proliferation and migration of vascular smooth muscle cells (VSMC) is one cholesterol-independent effect of statins which could lower the rate of in-stent restenosis (ISR) even if the exact mechanism remains unclear.The aim of this study was explore to the exact inhibitory mechanisms of simvastatin on ISR in vivo.

作者: WANG Yi-yong XU Wen-ke XIAO Wen-tao YU Jie LI Mu-wei

作者单位: People”s Hospital of Zhengzhou University First Affiliated Hospital of Zhengzhou University

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 258-258

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）