Expression of angiotensin-converting enzyme and angiotensin-converting enzyme 2 in patients with chronic heart failure
Background It has been reported that angiotensin converting enzyme 2 (ACE2) is an endogenous counter regulator of the rennin angiotensin aldosterone system (RAAS).However, the role of ACE2 in the development of human heart failure is not well established.Methods We evaluated the expression of angiotensin converting enzyme (ACE) and ACE2 at mRNA and protein levels in myocardium from 35 patients with mild or moderate to severe heart failure, and from seven cases with normal myocardium.
WANG Jiang LI Nan LI Ai-min SONG Rong GAO Feng GENG Zhao-hua ZHU Shan-jun
Institute of Cardiovascular Disease,Xinqiao Hospital
国内会议
北京
英文
259-259
2013-03-20(万方平台首次上网日期,不代表论文的发表时间)