Suppression of NF-kB reduces myocardial no-reflow

摘要：

Background No-reflow phenomenon is a risk factor which severely compromises the benefits of coronary revascularization in patients with acute myocardial infarction.Inflammatory response, as an essential component of cardiac ischemia/reperfusion (I/R) injury, has been suggested to contribute to the myocardial no-reflow.Since nuclear factor kappa B (NF-kB) is a key mediator of inflammation, we reasoned that inhibition of NF-kB might reduce the extent ofno-reflow.

作者: YAN Hong-bing ZENG Min CHEN Yi ZHAO Han-jun L(U) Yuan LIU Chen ZHOU Peng ZHAO Bo

作者单位: National Center for Cardiovascular Diseases,Cardiovascular Institute and Fuwai Hospital,Peking Union People”s Hospital of Hainan Province,Haikou,China Department of Cardiology,Beijing Anzhen Hospital,the Capital Medical University,Beijing,China

会议类型: 国内会议

会议名称: 第11届中国介入心脏病学大会

会议地点: 北京

会议语种:英文

页码: 260-260

在线出版日期: 2013-03-20（万方平台首次上网日期，不代表论文的发表时间）