The initial experimental study on the left ventricular function of pig with severe myocardial emergency contusion by DSCT
Objective To investigate the irregularity chang of the left ventricular functional after emergency severe myocardial contusion.Methods 16 BAMA experimental pigs were selected and striked to establish myocardial contusion model.Vital signs of these pigs were conventionally monitored, and DSCT scanning were performed at time points before striking, post striking immediately, 2h, 4h and 8h after striking.The index included ejection fraction (EF), the wall thickness of left ventricle at the end of systole and diastolic phase, and FS.The data was analyzed by ONE-WAY ANOVA.Results After severe myocardial contusion, the heart rate of pigs keeped lower, the breathing frequency lower lightly.While the mean arterial pressure (MAP) decreased immediately and increased gradually at 4h and 8h after myocardial contusion, the function of left ventricle changed obviously.The EF descend markedly, the descended rate was 18.8%, 21.3%, 16.74%, 5.3%,respectively, there are statistic difference between the 2h and that of before striking (P<0.05=.The wall thickness of the left ventricle at 2h is different from others.Conclusions DSCT is very usefully potential tool to evaluate the experimental myocardial contusion.Specially, the functional change of the left ventricular and the degree of injury of pigs could be assessed by DSCT after emergency myocardial contusion.
myocardial contusion left ventricular function strikking dual-source CT
Ou Shan-xing Long Fang Zhang Li Hua LI-dian Ou Shu-fei Li ye-kuo Peng Guang-ming Guo Yuan-xing Li xiao-rong Li Song-na
Department of Radiology,General hospital of Guangzhou military command, Guangdong ,Guangzhou ,510010, China
国内会议
广州
英文
555-558
2015-10-08（万方平台首次上网日期，不代表论文的发表时间）