Ultra Performance Liquid Chromatography-tandem Mass Spectrometry for the Determination of Amicarthiazol Residues in Soil and Water Samples
A reliable and rapid method has been optimized to determine the residue of amicarthiazol in soil and environmental water samples.After extraction and evaporation, the extraction was carried out with solid phase extraction (SPE) cleanup using HLB cartridge (only soil samples) and for the quantitative determination by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).The resulting residues of amicarthiazol were analyzed by a gradient separation performed on a UPLC system with a C18 column, methanol and water containing 0.1% (v v-1) formic acid as the mobile phase in the mode of electrospray positive ionization (ESI+) and multiple reaction monitoring (MRM).Results showed that the recoveries for spiked samples were 74.4-97.1% and 72.1-109.9% for soil and water, respectively, with the relative standard deviation (RSD) less than 10.2% when fortified at 10, 100 and 1000 ag L-1.The limits of detection (LODs) and the limits of quantification (LOQs) for matrix matched standards ranged from 0.073-0.425ag L-1 and 0.243-1.42 μag L-1.The intra-day precision (n=5) and the inter-day precision over 10 days (n=10) for the amicarthiazol in soils and water samples spiked at 100 ag L-1 was 7.9% and 15.9%, respectively.Results indicated that the developed method could be a helpful tool for the controlling and monitoring of the risks posed by amicarthiazol to human health and environment safety.
amicarthiazol solid phase extraction ultra performance liquid chromatography-tandem mass spectrometry soil water
Tian Chun-xia Gui Wen-jun Tian Jie Li Shu-ying Ma You-ning Zhu Guo-nian
Institute of Pesticide and Environmental Toxicology,Zhejiang University,268 Kaixuan Road,Hangzhou 31 Zhenjiang Institute of termite control,65 Yunhe Road,Zhengjiang,212003,China
国内会议
第十四届全国农药学科教育科研研讨会暨赵善欢学术思想与研究实践讨论会
广州
英文
63-75
2014-08-03（万方平台首次上网日期，不代表论文的发表时间）