DNA Methylation Profiles related with beef Tenderness in Angus Cattle
Tenderness constitutes one of the main characteristics in beef quality.In this study, a methylome analysis was performed in closed Wye Angus steers with genetically homogenous phenotypic backgrounds.Through the use of the Methyl CpG Binding Domain protein-enriched genome sequencing (MBD) method,differentially methylated regions (DMRs) were identified and annotated, respectively.Among 1,576 identified DMRs, 983 were downregulated and 593 were upregulated in the ”tender” group, demonstrating a global decrease in DNA methylation.We then depicted the DNA methylation profiles in each chromosome, functional regions of genes, etc.The results from the research provide new insights to the epigenetic factors affecting beef quality.
DNA methylation Beef tenderness Cattle Meat quality
Chunping Zhao José A.Carrillo Yaokun Li Linsen Zan Jiuzhou Song
College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China;Departm Department of Animal & Avian Sciences, University of Maryland, College Park, MD, USA College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China
国内会议
陕西杨凌
英文
82-87
2015-11-16（万方平台首次上网日期，不代表论文的发表时间）