Transcriptomic profiling of rumen in grass-fed and grain-fed Angus cattle

摘要：

　　Rumen is important to digest forage constituting a critical step to supply enough nutrients for animals”growth and production.In this study, we hypothesize that rumen may function differently in grass-and grain-fed regimens.The objective of this study was to find the differentially expressed genes in the ruminal wall of grass-fed and grain-fed steers, and then explored the potential biopathways.Thereby, the RNA Sequencing(RNA-Seq) method was used to measure the gene expression level in the ruminal wall.The analysis totally detected 342 differentially expressed genes between ruminal wall samples of beef raised under different regimens.The Ingenuity Pathway Analysis (IPA) analysis found 13 significantly enriched pathways, most of which were related to cell development and biosynthesis.Our results provided valuable insights into the molecular mechanisms resulting in the phenotype difference between grass-fed and grain-fed cattle.

关键词： RNASeq Gene expression Rumen genes Grass-fed cattle Grain-fed cattle Rumen transcriptome Transcriptomic analysis

作者: Yaokun Li José A.Carrillo Yi Ding YangHua He Chunping Zhao Linsen Zan Jiuzhou Song

作者单位: College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi,P.R.China, 712 Department of Animal & Avian Sciences, University of Maryland, College Park, MD 20742, USA

会议类型: 国内会议

会议名称: 2015第三届中国肉牛选育改良与产业发展国际研讨会

会议地点: 陕西杨凌

会议语种:英文

页码: 121-128

在线出版日期: 2015-11-16（万方平台首次上网日期，不代表论文的发表时间）