Novel Polymorphism of the Bovine FTO Gene are Related to Backfat Thickness and Longissimus Muscle Area in Five Chinese Native Cattle Breeds
In this study, genetic variation of the fat mass and obesity-associated gene (FTO) was detected by PCR-SSCP and DNA sequencing in 618 individuals from five Chinese indigenous cattle breeds, and their genetic effects on meat quality traits were evaluated.The results showed that a novel single nucleotide polymorphism C1071T was detected in exon 5 and the allelic frequencies for the C and T alleles of the five breeds were 0.666/0.334; 0.583/0.417; 0.631/0.369; 0.653/0.347; 0.689/0.311,respectively.Animals with CT genotype had higher mean values for backfat thickness than those with CC or TT genotypes (P < 0.01).Individuals with CC or CT genotypes had higher Iongissimus muscle area than those with TT genotype (P < 0.05).The FTO gene may be a candidate gene for identifying differences in meat quality traits and therefore could be applied to marker-assisted selection of native Chinese cattle breeds.
Cattle FTO gene SNP meat quality traits
Shengjuan Wei Linsen Zan Javed Ahmed Ujan Hongbao Wang Yanjie Yang Camus Adoligbe
College of Animal Science and Technology, Northwest A&F University, Shaanxi, 712 100, P.R.China College of Animal Science and Technology, Northwest A&F University, Shaanxi, 712 100, P.R.China;Nati College of Life Sciences, Henan Normal University, Xinxiang, Henan, 453007, P.R.China
国内会议
陕西杨凌
英文
215-221
2011-05-01（万方平台首次上网日期，不代表论文的发表时间）