Polymorphism of Somatostatin Gene and Its Association with Growth Traits in Chinese Cattle
Somatostatins play a crucial role in the regulation of growth and development in vertebrates,especially muscle growth.We assessed the association of somatostatin gene polymorphisms with growth traits by PCR-SSCP (polymerase chain reaction-single strand conformation polymorphism) and DNA sequencing methods in 694 individuals from six Chinese cattle breeds.A novel single nucleotide polymorphism, G126A, was detected, and significant associations were found with body length, body height, hip width, heart girth, and hucklebone width index.Polymorphism of the somatostatin gene was found to be highly associated with growth traits in the Qinchuan breed at various ages.Gene frequency analysis showed significant differences among the breeds.Individuals with genotype AA had significantly lower body height, body length, hip width, and hucklebone width values compared to AG at 1.5 years old, and had significantly lower hip width, body length and hucklebone width compared to AG at 2 years old.At 2.5 years old, populations with genotype AA had significantly lower body length,hip width and hucklebone width than AG individuals, with the exception of the Luxi breed, in which two genotypes were found.The Luxi and Ximentaer crossbreed had the lowest frequency of the G allele, while the highest G allele frequencies were found in the Luxi breed.
Cattle SST gene PCR-SSCP Growth traits SNPs
Li Gao Linsen Zan Hongbao Wang Rui Jie Hao Xin Zhong
College of Animal Science and Technology, Northwest A&F University,Yangling, Shaanxi, P.R.China College of Animal Science and Technology, Northwest A&F University,Yangling, Shaanxi, P.R.China;Nati
国内会议
陕西杨凌
英文
251-258
2011-05-01（万方平台首次上网日期，不代表论文的发表时间）