New anti-cancer drug candidate: ”CuⅡ(methyl-substituted-phen)L” complexes
In order to seek better anticancer drug, choosing phen and methyl-substituted-phen as predominant ligands, we synthesized two series near hundred complexes ”Cu(phen)L” and ”Cu(methyl-substituted-phen)L” (L are ligands with O or N).Screen revealed that the both series show excellent anticancer activities against cancerlines such as A-549, Be1-7402, HCT-8, MDCK and L-1210 cells in vitro, and H22 and Lewis in vivo.
Lu Xiaoming Wang Shuo Chen Yuyou Xia Sifeng Cheng Yifeng Sun Xiaojing Zhang Bo Zhang Weichuan
Panganghuo Capital Normal University,Beijing 100048,China
国内会议
昆明
英文
110-110
2015-07-24(万方平台首次上网日期,不代表论文的发表时间)