Viral Etiology of acute respiratory tract infections in hospitalized children and adults in Shandong Province, China

摘要：

　　Background: The dominant viral etiologies responsible for acute respiratory infections (ARIs) are poorly understood, particularly among hospitalized patients.Improved etiological insight is needed to improve clinical management and prevention of ARIs.Methods: Clinical and demographic information and throat swabs were collected from 607 patients from 2011 to 2013 in Shandong Province, China.Multiplex RT-PCR (SeeplexTM RV detection, Seegene) was perfomed to detected 12 respiratory viral pathogens.Results: A total of 607 hospitalized patients were enrolled from 2011 to 2013.Viruses were identified in 35.75% (217/607) of cases, including influenza virus (18.75%), PIVs (18.36%), RSV (16.02%) and ADV (14.84%).For the children under 14 year old, the common detected viruses were influenza viruses, RSV, PIVS and ADV, while the principal respiratory viruses were HCoV, PIVs, influenza viruses for the old adults.Co-infections with multiple viruses were detected in 15.67% of patients.Children under 5 years were more likely to have one or more detectable virus associated with their ARI.The peak of ARI caused by the respiratory viruses occurred in winter.Conclusion: Respiratory viral infections, particularly influenza virus, RSV and ADV, were associated with high rates of illness and make up a substantial portion of respiratory infection in Shandong hospitalized patients.Our data can help develop health policy for effective prevention of respiratory virus infection.

关键词： hospitalized patients acute respiratory virus infection etiology epidemiology

作者: Ti Liu Zhenqiang Bi Xianjun Wang Zhong Li Shengyang Zhang Shaoxia Song Wu Julong Yi Lin Nongjian Guo Chunyan Xing Aiqiang Xu

作者单位: Shandong Center for Disease Control and Prevention, Shandong Provincial Key Laboratory of Infectious inan Central Hospital Affiliated to Shandong University, Jinan, 250014, Shandong, China

会议类型: 国内会议

会议名称: 世界中医药学会联合会中医药抗病毒研究专业委员会第一届学术年会

会议地点: 烟台

会议语种:英文

页码: 381-392

在线出版日期: 2015-07-01（万方平台首次上网日期，不代表论文的发表时间）