Diagnosis and Treatment Regularity of Traditional Chinese Medicine for Syndrome Factors of SLE: a Literature Research based on Shannon Entropy Method
Objective: To explore and investigate the diagnosis and treatment regularities for syndrome factors of SLE by analyzing the clinical literature of Traditional Chinese Medicine (TCM) and Chinese integrative medicine basing on data mining method.Methods: The literature that met the inclusion criteria were screened out from the China National Knowledge Internet (CNKI) and the Chinese Biomedical Literature Database (CBM).After preprocessing the data from the qualified literature, the method of Shannon entropy nonlinear complex system of engineering software Matlab 7.0 was applied to extract the features association of symptoms and Chinese medicine.Results: The six syndrome factors of disease nature with the highest frequency were yin deficiency, heat, toxic, blood stasis, qi deficiency, yang deficiency;the top three syndrome factors of disease location with the highest frequency were kidney, spleen and liver.Rehmanntae, Moutan, Poria, etc, were with the highest Chinese medicine utilized frequency among all the Chinese medicine that was retrieved from 413 recipes.At the same time, we obtained two preferred collections of symptoms and Chinese medicine by exploring the extraction that was based on features associated among major syndrome factors, symptoms and Chinese medicine.The relationship between syndrome factors and symptoms was in accordance with the theory of TCM, and the relationship between syndrome factors and Chinese medicine was in line with the traditional efficacies of Chinese medicine.Conclusions: Basing on the method of relational grade analysis of Shannon entropy nonlinear complex system, the diagnosis and treatment regularities of symptoms-syndrome factors-Chinese medicine that provides the frame and theory for the research of standardization of SLE syndrome are explored.
entropy traditional Chinese medicine Systemic Lupus Erythematosus syndrome factors regularity
梁碧欣 吴元胜 禤国维 骆颖翔
国内会议
杭州
英文
144-152
2015-05-22（万方平台首次上网日期，不代表论文的发表时间）