Evaluation of the Pathological Grade in Gliomas:Application of DSC-PWI
objective Assessment of DSC-PWI For gliomas preoperative value of histological grade.Materials and Methods 76 cases gliomas confirmed by surgery and pathology were analyzed,36 cases of low-grade(grade Ⅰ~Ⅱ),40 cases of high-grade(grade Ⅲ~Ⅳ),all cases underwent conventional MRI plane scan,contrast MRI scan and DSC-PWI.Maximum rCBV values of solid part(the solid part to the corresponding contralateral normal white matter ratio)are caculated.Comparison of maximum rCBV values of tumor different levels was assessed by t test.Drawing ROC curve to determine the ideal value of rCBV threshold between high-grade and low-grade gliomas.Results The maximum value of rCBV in the solid part of gliomas are related positively with pathological levels,the maximum rCBV values of high-grade and low-grade gliomas were 0.87411±0.935、2.0415±1.5311 respectively,significant difference were showed among all grades of gliomas(P=0.002).To identify the high level and low-grade gliomas,1.35 as the ideal threshold,the AUC value 0.73911.the sensitivity and specificity were 66.7% ,73.0% .Conclusion rCBV examination will be able to assess the level of tumor pathology.PWI examination for preoperative evaluation of gliomas have a higher value of histological grade.
glioma DSC-PWI rCBV
Wang Ying QI Jianping
Department of Radiology,Tonji Hospital,Tongji Medical College of Huazhong University of Science and Department of Radiology,Tonji Hospital,Tongji Medical College of Huazhong University of Science and
国内会议
北京
英文
1-2
2015-12-18（万方平台首次上网日期，不代表论文的发表时间）