BMSCs paracrine repairs smoke inhalation injury: angiogenesis involving Notch signaling pathway

摘要：

　　Smoke inhalation injury is acute lung injury induced by smoke exposure characterized by vascular endothelial injury and increased permeability.Cell therapy is an attractive new therapeutic approach, though its underlying mechanism and signaling pathway remain poorly understood.We investigated the effect of systemic transplantation of preconditioned bone marrow-derived mesenchymal stem cells (BMSCs) on angiogenesis in rat model of smoke inhalation injury, and explore the underlying mechanism and possible signaling pathway.

关键词： smoke inhalation injury bone marrow-derived mesenchymal stem cells paracrine angiogenesis Notch

作者: Feng Zhu Junjie Wang Yichao Jin Xiaochen Qiu Jiahui Li Zhaofan Xia

作者单位: Burns Institute of PLA,Changhai Hospital,Second Military Medical University,Shanghai,China 200433;De Burns Institute of PLA,Changhai Hospital,Second Military Medical University,Shanghai,China 200433 Department of Pathology,Kunming Medical College,Kunming,China 650000

会议类型: 国内会议

会议名称: 中国医师协会创伤外科医师分会成立筹备大会、第八届全国创伤外科学术研讨会暨第二届阳明危重病急救医学论坛

会议地点: 浙江余姚

会议语种:英文

页码: 330-331

在线出版日期: 2014-10-16（万方平台首次上网日期，不代表论文的发表时间）