Low Frequency Electromagnetic Field Promotes Growth and Anagen Progression of Hair Follicles
Object: Many studies suggested that low frequency electromagnetic field (LFEMF) was useful for early healing of wound.Wound healing involve in cutaneous appendage neogenesis such as hair follicle (HF).But LFEMF bioeffects on HF growth have not been fully elucidated.This present study was designed to determine the effects of EMF on hair growth and the role of epidermal stem cells.Methods: C57BL/6 mice were used to make the model of depilation-induced HF cycling,and divided at random into the control group and LFEMF group,and then harvested the skin specimens to assess for hair growth,hair anagen progress and Cytokeratin 15 (CK15) expression.Results: The results showed that,compared to the control,the length and size of hair follicles clearly increased at 9day and 16day,and anagen progression delayed in 1-3days in depilation-induced hair cycle progression,and CK15 expression increased in the follicular bulge region in the LFEMF group.Conclusions: LFEMF was shown to participate in the regulation of the mouse hair growth cycle and could promote the proliferation of the bulge stem cells.
Low frequency electromagnetic field Hair growth Cycle
Xinping Li Mingsheng Zhang Xin Wang Liming Bai Pin Zhao Hongxiang Zhu Bo Wu Weicheng Xu Wenfang Bai Yan Ye
Department of Physical Medicine and Rehabilitation,Guangdong Geriatric Institute,Guangdong Academy o The First Clinical College of Jinan University,Guangzhou 510632,China Changsha medical school,Changsha,410219,China
国内会议
第四届粤港澳台物理医学与康复学学术会议暨2013年广东省医学会物理医学与康复学学术会议
广州
英文
210-214
2013-08-16（万方平台首次上网日期，不代表论文的发表时间）