The research of the vesicle - bilayer - vesicle transition of phospholipid induced by macromolecular surfactant
Lipid vesicle was prepared by ultrasonic method and formed supported lipid bilayers on SiO2 surface. The anionic polyelectrolyte with hydrophobic end group was introduced, then the hydrophobic end insert into the bilayer and cause the bilayer curl by the electrostatic interaction between the lipid molecule and the polyelectrolyte. The curling bilayer further formed new vesicle with the polyelectrolyte embedded inside. It is the first time to implemente the vesicle - bilayer - vesicle transition of phospholipid on SiO2 surface. The mechanism of the transition was studied by the combination of QCM - D with ellipsometry.
macromolecular surfactant lipid bilayer vesicles polyelectrolyte quartz crystal microbalances
国内会议
上海
英文
167-173
2014-04-01(万方平台首次上网日期,不代表论文的发表时间)