Two new natural products from the root of Raphanus sativus L.
The roots of Raphanus sativus L., also called radish, has been used as a traditional anti-migraine drug in China for hundreds of years.However, its bioactive substances and pharmacological mechanism were still not very clear.In this study, two.new natural products were isolated from the roots of Raphanus sativus L.by successive chromatographic procedures, such as open silica gel, Sephadex LH-20 and open RP-18 column chromatograph.The structures of isolated compounds were elucidated as Cis-(1-methylazetidin-2-yl)methanol and cyclo-(4-methyl-Val-4-methyl-Val) on the basis of spectral data analysis, including MS and NMR (1H-NMR, 13C-NMR, NOESY, HSQC and HMBC).The new natural products would be potential candidates for early anti-migraine drug study.
Raphanus sativus L. New natural products Spectroscopic characterization
WANG Feng CHEN Huan WANG Yi-bo LIANG Sheng-wang WANG Shu-mei
College of Traditional Chinese Materia Medica, Guangdong Pharmaceutical University, and the Key Unit of Chinese Medicine Digitalization Quality Evaluation of SATCM, Guangzhou 510006, China
国内会议
广州
英文
416-419
2014-11-01（万方平台首次上网日期，不代表论文的发表时间）