Prescription Pattern of Therapeutic Agents against Systemic Lupus Erythematosus at the Outpatient Clinic in a Tertiary Care Teaching Hospital
Background: A wide range of medications are now available for the treatment of systemic lupus erythematosus (SLE).Selection of the optimal treatment combination of agents is essential for patients with satisfactory clinical condition who visit outpatient clinics.Objectives: This study was designed to evaluate the drug prescribing pattern for SLE at the outpatient clinic in a tertiary care teaching hospital in South China.Methods: A total of 973 prescriptions from patients diagnosed with SLE for treatment were randomly selected in the chosen outpatient health facility between May and October 2013.Data on demographic characteristics and prescribed medication were collected and analyzed.Results: Analysis of the data revealed that more female (n=856) than male (n=117) were diagnosed with SLE.Of the 973 patients studied,13.1% (n=127) were on monotherapy and 86.9% (n=846) on combination therapy.Of the patients on combination therapy,19.5% (n=190),25.7% (n=250),21.5% (n=209) and 20.2% (n=197) were on 2,3,4 and more than 4 drugs,respectively.The most commonly used therapeutic groups were immunosuppressant (74.0%),glucocorticoids (68.3%),and the antimalarial agent hydroxychloroquine (47.2%).Overall,prednisone were prescribed the highest (55.6%) followed by hydroxychloroquine (47.2%),methotrexate (36.3%),meprednisone (12.7%),and ciclosporin (12.2%).Conclusions: Prescribing pattern of therapeutic agents against SLE showed adherence to existing evidence based guidelines.Special Attention should be paid for the adjustment of individualized dosage regimen and rational usage of glucocorticoids and immunosuppressive agents in the treatment of SLE.
Prescription patterns SLE Outpatients
Chenshu Xu Ting Zhu Liyi Feng Dongxia Cui Xiao Chen
Department of Pharmacy,The First Affiliated Hospital of Sun Yat-sen University,Guangzhou,Guangdong,China 510080
国内会议
大连
英文
118-126
2014-06-01（万方平台首次上网日期，不代表论文的发表时间）