Heat stress induces GDF9, GDF15, Pdgfa, Vegfa, Alb, Egfr expression in rat small intestine and in rat IEC-6
”Aims” :The present study was to detect the expression of GRFs when suffering heat stress both in vivo and in vitro.”Method” :We employed GRFs expression with Realtime-PCR and morphological changes in response to heat stress in vivo and vitro.”Result” : Heat stress treatment leaded to intestinal mucosal epithelial shedding,exposing the lamina propria.The genes expression of Growth differentiation factor 9 (GDF9), Growth differentiation factor 15 (GDF15), platelet-derived growth factor a (Pdgfa) and vascular endothelial growth factor A (Vegfa) were significantly increased after heat stress.On the contrary,gene expressions of albumin (AIb) and epidermal growth factor (Egfr) were decreased after heat stress.”Conclusion” :Heat stress induced GRFs including GDF9, GDF15, Pdgfa,Vegfa,Aib, Egfr expression both in rat small intestine and in rat IEC—6 cells.
heat stress rat IEC-6 cell lines growth related genes
CH.MEI F.H.LIU J.Q.Xu H.ZHAO P.CHENG L.XU Y.J.BAI X.L.XU X.H YU X.L CHONG J.J.CHEN
Beijing Key Laboratory for Dairy Cow Nutrition ,College of Animal Science and Technology,Beijing Uni College of Veterinary Medicine, China Agricultural University (CAU), Beijing 100193, P.R.China
国内会议
第四届京津冀一体化畜牧兽医科技创新研讨会暨“瑞环杯”新思想、新方法、新观点论坛
石家庄
英文
146-150
2014-10-24（万方平台首次上网日期，不代表论文的发表时间）