The Polymorphisms of SIRT2 Gene and Their Association with Body Measurement and Ultrasound traits of Qinchuan Cattle
SIRT2 (silent information regulator 2) is a member of the Sirtuin family class Ⅲ NAD (nicotinamide adenine dinucleotide)-dependent protein deacetylases and has an important role on senescence, metabolism and apoptosis.The objectives of this study were to detect bovine SIRT2 gene polymorphisms and analyze the relationship with meat quality and body measurement traits in Qinchuan cattle.Altogether, four SNPs in the 4 intron, 4 exon, 9 exon and 12 exon of SIRT2 gene were identified by sequencing in 520 Qinchuan cattle.Association analysis showed that these four mutations were significantly correlated with body measurement and meat quality traits.When in combination, the H1H1 (AA-CC-GG-CC) diplotypes had better performance than other combinations.These results provided evidence that SIRT2 gene could be a candidate for marker-assisted selection in Qinchuan cattle breeding program, and that SIRT2 might be involved in the regulation of cattle growth and meat quality.
SIRT2 gene body measurement ultrasound traits cattle
Linsheng Gui Wucai Yang Chunpin Zhao Zhidong Zhao Linsen Zan
College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, P.R.C College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, P.R.C
国内会议
第二届中国肉牛选育改良与产业发展国际研讨会暨中国畜牧兽医学会养牛分会八届二次学术研讨会
陕西杨凌
英文
242-250
2013-10-22（万方平台首次上网日期，不代表论文的发表时间）