Effects of Pharmaceutical Care Interventions on Blood Pressure and Medication Adherence of Patients with Primary Hypertension in China
Objective: To assess the effects of pharmaceutical care interventions on blood pressure (BP) and medication adherence of patients with primary hypertension in China.Methods: A total of 60 patients with primary hypertension were enrolled in the trial for a 12-month period.Participants were randomized to either control group or intervention group in a 1∶1 ratio.During the follow-up period, patients in control group were given regular medi-care, while patients in intervention group accepted pharmaceutical care.The dates of baseline demographics, medication lists, measurement of medication adherence, BP values were collected.Statistical analyses were conducted using t test or x2 test.Results: After 12 months follow-up, 24-hour BP was significantly decreased 9.75 mmHg (7.1%) for systolic blood pressure (SBP) and 5.88 mmHg (6.6%) for diastolic blood pressure (DBP) in the intervention group (p<0.05) compared with their initial visit, while there is no significant change in the control group (p>0.05).The intervention group demonstrated a higher percentage of patients with high adherence (72.41%) at 12 months, whereas control group hardly had changes in medication compliance.Conclusion: Our results indicate that pharmaceutical care intervention might contribute to better BP control of primary hypertension, and could enhance medication compliance of patients.
primary hypertension antihypertensive therapy pharmaceutical care medication adherence
Jinping Wang Fei Peng Jianlong Wu Junfen Yang Yihao Zhuang Jialin Chen Wenjing Qian Jie Tian Xiaoyan Chen Dingping She
Department of Pharmacy,the Second People”s Hospital of Shenzhen,518035,China Department of Cardiology,the Second People”s Hospital of Shenzhen,518035,China
国内会议
2012深圳市中西医结合学会虚证与老年病专业委员会、深圳市中医药学会老年病专业委员会学术年会
深圳
英文
135-149
2012-12-01（万方平台首次上网日期，不代表论文的发表时间）