Carbonic anhydrases Ⅲ and Ⅳ auto-antibodies in rheumatoid arthritis, systemic lupus erythematosus, diabetes, hypertensive renal disease and heart failure

摘要：

　　Carbonic anhydrases (CA) Ⅲ and Ⅳ play critical roles in maintaining the intercellular/extrace!lular pH and scavenging oxygen radicals in mammalian cells.In present study, the CA Ⅲ and Ⅳ auto-antibodies, the CA activity, the antioxidant enzymes and cytokines in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), diabetes, hypertensive renal disease and heart failure were investigated.The anti-CA m antibody titers in patients with RA, SLE and type Ⅰ diabetes (T1D) were significantly higher than that in control groups (P<0.05).

关键词： carbonic anhydrases Ⅲ auto-antibody carbonic anhydrases Ⅳ auto-antibody autoimmune oxidative stress

作者: Chengeng Liu Yue Wei Jianmin Wang Langan Pi Jianjun Huang Peichang Wang

作者单位: Department of Clinical Laboratory,Xuanwu Hospital,Capital Medical University.Beijing,100053,People”s Department of oncology,Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,Peopl Department of Clinical Immune,Xiangya School of Medicine.Central South University,Changsha,410078,Hu

会议类型: 国内会议

会议名称: 2012北京检验医学年会暨中青年检验医学论坛

会议地点: 北京

会议语种:英文

页码: 194-202

在线出版日期: 2012-10-01（万方平台首次上网日期，不代表论文的发表时间）