Anti-bacterial properties of wool fabric immobilizing lactoferrin via microbial transglutaminase
In this paper,a new biological cross-linker,microbial transglutaminase (mTGase) was used to catalyze the immobilization of lactoferrin onto the wool fabrics and the antibacterial properties of wool immobilizing lactoferrin,which shows antimicrobial activity on both Gram-negative and Gram-positive bacteria,were determined.It was found that the minimal inhibitory concentration (MIC) of lactoferrin against S·aureus and E·coli is 0.5mg/mL and 0.25mg/mL.Compared with the control sample,the amount of lactoferrin adhered onto the wool fabric was improved from 4.87 mg·(g fabric)-l to 12.96 mg(g fabric)-1.That means the crosslinking reaction initiated by mTGase can mcrease the amount of lactoferrin fixed onto wool fabric obviously.The ratios of bacteriostasis to S.aureus and E.coli of wool fabrics immobilizing lactoferrin reached 57.95% and 69.96%,respectively,showing good antibacterial property.
transglutaminase lactoferrin antibacterial wool
Han Xue Wang Qiang Fan Xuerong Yu Yuanyuan Yuan Jiugang Cui Li Wang Ping
Key Laboratory of Science and Technology of Eco-Textile,Ministry of Education,Jiangnan University,Wuxi,Jiangsu 214192,China
国内会议
无锡
英文
811-820
2013-10-25（万方平台首次上网日期，不代表论文的发表时间）