Phosphorescent Conjugated Polyelectrolytes for Nanoscale Biodetection by Time-Resolved Techniques
We report for the first time the use of time-resolved technique in biodetection based on the phosphorescent conjugated polyelectrolytes (PCPEs) in both aqueous environment and cell to eliminate autofluorescence and enhance S/N ratio.A PCPE-based heparin probe with low detection limit,high selectivity and naked-eye detection is realized.Quantifications for heparin are achieved in the range of 0-70 μM and 0-5 μM in water and in serum.This PCPE-based assay may open up a new perspective for designing promising phosphorescent materials for biosensor.
Huifang Shi Shujuan Liu Qiang Zhao Wei Huang
Key Laboratory for Organic Electronics & Information Displays(KLOEID)and Institute of Advanced Materials(IAM),Nanjing University of Posts and Telecommunications,Wenyuan Road 9,Nanjing City,Jiangsu Province,210046 China
国内会议
南京
英文
1-5
2012-06-08（万方平台首次上网日期，不代表论文的发表时间）