Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle loading daunorubicin and bromotetrandrine in nude mice bearing leukemia tumor xenografts

摘要：

　　Objective This paper was to study the reverse effect of magnetic Fe3O4 nanoparticle loading daunorubicin and bromotetrandrine (Fe3O4-MNPs/DNR/BrTet) with the conduction of alternating magnetic field in nude mice bearing K562/A02 xenografts, and to provide theoretic evidence for the clinical application of malignancies as a new treatment.Methods 25 BALB/c nude mice with equivalent different gender which were age-matched(four weeks of age) and weight-matched(16-22g) were randomly divided to 5 groups.

作者: KEN Yanyan DING Jiahua GAO Chong WANG Jun BAO Wen WANG Lei TIAN Liang SONG Huihui WANG Xuemei CHEN Baoan ZHANG Haijun CHENG Jian CAI Xiaohui LIU Ran XIA Guohua WU Weiwei WANG Shuai

作者单位: Department of Hematology and Oncology key Medical Discipline Jiangsu Province 210009;Zhongda Hospita Zhongda Hospital,Medical School, Southeast University;Faculty of Oncology, Medical School, Southeast

会议类型: 国内会议

会议名称: 第八届全国难治性白血病学术研讨会、第四届全国难治性淋巴瘤学术研讨会、第四届全国多发性骨髓瘤学术研讨会、第五届钟山国际MDS学术研讨会、南京2012血液学年会

会议地点: 南京

会议语种:英文

页码: 189-190

在线出版日期: 2012-05-01（万方平台首次上网日期，不代表论文的发表时间）