Relationship between aspirin and clopidogrel resistance in acute coronary syndrome
Objectives We have prospectively investigated the association between aspirin and clopidogrel low responsiveness.Methods 635 Non ST Elevation Acute Coronary Syndrome (NSTE ACS) patients were included and received loading doses of 300 mg aspirin and 600 mg clopidogrel.We analyzed posttreatment maximal intensity of arachidonic acid and ADP—induced platelet aggregation (AAAg and ADPAg) and Platelet Reactivity Index of VAsodilatorStimulated Phosphoprotein (PRI VASP).Aspirin and clopidogrel low responsiveness were defined respectively by AAAg > 30% and ADPAg > 70%.
Hua Shen Yujie Zhou Yuyang Liu Fei Gao Shiwei Yang Zhijian Wang Zhenxian Yan Hongya Han
Beijing Anzhen Hospital affiliated to Capital Medical University Beijing Institute of heart lung and blood vessel diseases
国内会议
北京
英文
98-98
2013-04-19(万方平台首次上网日期,不代表论文的发表时间)