The monitoring and preventing of spinal cord ischemic injury during thoracic descending aortic operating
Background A model of ischcmic injury to the spinal cord was established in pigs by clamping the thoracic descending aorta.The feasibility of monitoring spinal-cord ischemia using the cortical somatosensory evoked potential (CSEP) was evaluated.Outcomes between the simple clamp (SC) group and left-heart bypass (LHB) group were compared.Methods Twelve mini-pigs were randomly divided into two groups SC group and LHB group randomly.The left intercostal incision was adopted.The thoracic descending aorta was clamped under the left irmominate artery outlet.CSEP was recorded to monitor the function of the spinal cord.The behavior score was observed every day after surgery.Mini-pigs were killed on the seventh postoperative day.Ultrastructural changes were observed by transmission electron microscopy.
cortical somatosensory evoked potentials spinal cord ischemia paralysis paraplegia left heart bypass
Feng Liu Yulong Guan Caihong Wan Peiqing Dong
Extracorporeal Circulation Department, Beijing Anzhen Hospital, Capital Medical University, Beijing.China, Department of Extracorporeal Circulation, Fuwai Hospital, Beijing, China
国内会议
北京
英文
131-131
2013-04-19（万方平台首次上网日期，不代表论文的发表时间）