Role of serum activity of matrix metalloproteinase-9 in restenosis rate after implantation of drug-eluting stents

摘要：

　　Background Despite the popularity of coronary stenting in coronary artery disease (CAD).restenosis remains a challenging clinical problem.We aim to test whether serum level of matrix metalloproteinase (MMP)-9 is associated with the development of instent restenosis (ISR) in patients treated with drug—eluting stents (DES).Methods 120 patients who were treated with DES were enrolled into our study.Blood samples for measurement of MMP-9 antigen and activity were taken directly before and 48h after percutaneous coronary intervention (PCI).Restenosis was evaluated at 9-12 months by coronary angiography.

作者: Dong-mei Shi Yu-jie Zhou Yu-yang Liu Hong-ya Han

作者单位: Beijing Anzben Hospital of Capital Medical University, Beijing institute of heart lung and blood vessel diseases

会议类型: 国内会议

会议名称: 第七届北京五洲心血管病研讨会

会议地点: 北京

会议语种:英文

页码: 141-141

在线出版日期: 2013-04-19（万方平台首次上网日期，不代表论文的发表时间）