奈米金探针应用於区分肺结核杆菌之方法
The Mycobacterium tuberculosis (MTB) shows different virulence and host infection range from other members of the M. tuberculosis complex (MTBC).Differential identification of MTB from MTBC is thus important in certain occasions.Many molecular diagnosis assays were developed that means the more advantages using molecular diagnosis than using conventional diagnosis in clinical specimens. In this study,we developed the diagnosis method that utilizes gold nanoparticles derivatized with thiol modified oligonucleotides that are designed to hybridize specifically complementaryDNA targets. Two pairs of gold nanoparticles probes, GP-IS6110 and GP-rv3618, aredesigned to specifically hybrid with target DNA of MTBC and MTB strains, respectively.
肺结核杆菌 奈米金探针 诊断方法 临床应用
Yu-Tze Horng 洪育芝 Po-Chi Soo 苏伯琦
Graduate School of Biotechnology and Bioengineering,Yuan Ze University,135 Yuan-Tung Road,Chung-Li 3 台湾 元智大学 生物科技与工程研究所
国内会议
西安
中文
876-876
2008-10-01（万方平台首次上网日期，不代表论文的发表时间）