Investigation of the extracts from Bidens pilosa Linn.var.radiata Sch.Bip.on chemical constituents and for antioxidant activities and cytotoxicity against human tumor cells

摘要：

　　The aim of this study was to evaluate antioxidant activities and cytotoxicity against human tumor cell lines of extracts from Bidens pilosa Linn.var.radiata Sch.Bip.(BP).The antioxidant properties of different polarity fractions extracted from BP were evaluated using DPPH and ABTS radical scavenging test and FRAP assay.The ethyl acetate fraction (EE-BP) showed the highest antioxidant activity compared to other fractions.In addition,the EE-BP displayed the most remarkable anti-proliferative effect against the tumor cells,particularly RKO cell in dose-and time-dependent manner.The antioxidant activities and cytotoxicity correlated highly with the total phenolic and flavonoid contents,respectively.

关键词： Bidens pilosa Linn.var.radiata Sch.Bip. Antioxidant activity Cytotoxicity Chemical constituent Colorectal cancer

作者: Jianguo Wu Zhongxian Wan Yanbin Wu Xiuhong Zou Jinzhong Wu

作者单位: Academy of Integrative Medicine,Fuj ian University of Traditional Chinese Medicine,Fuzhou 350108,P.R Department of Pharmacy,Fujian University of Traditional Chinese Medicine,Fuzhou 350108,P.R.China Forestry Bureau of Yongchun County,Yongchun,Fujian 362600,P.R.China Academy of Integrative Medicine,Fuj ian University of Traditional Chinese Medicine,Fuzhou 350108,P.R

会议类型: 国内会议

会议名称: 第六届中国民族植物学学术研讨会暨第五届亚太民族植物学论坛

会议地点: 银川

会议语种:英文

页码: 91-101

在线出版日期: 2012-08-05（万方平台首次上网日期，不代表论文的发表时间）