MTA3 and the Mi-2/NuRD complex regulates EMT in esophageal squamous cell carcinoma through chromatin remodeling pathway

摘要：

　　Epithelial-mesenchymal transition (EMT) is a key regulator for morphogenesis during embryonic development and the essential contribution of the EMT to carcinoma progression is the loss of their epithelial characters,gain of mesenchymal marker expression,acquisition of migration,invasive activity and capability to pass through the basement membrane.Chromatin remodeling pathways are critical in the regulation of cancer-related genes and are currently being explored as potential targets for therapeutic intervention.

作者: Jinfeng Gan Weiwei Li Xiaoxuan Zheng lin Zheng Yuping Chen Hao Zhang

作者单位: Cancer Research Center and Cancer Hospital,Shantou University Medical College,Shantou,Guangdong,China 515041

会议类型: 国内会议

会议名称: 2012医学科学前沿暨第二届个体化治疗与抗肿瘤药物研究新趋向研讨会

会议地点: 深圳

会议语种:英文

页码: 412-412

在线出版日期: 2012-07-13（万方平台首次上网日期，不代表论文的发表时间）