First evidence of proteinG-binding protein in the most primitive vertebrate:Serum lectin from lamprey(Lampetra japonica)

摘要：

　　Intelectins are a recently identified extracellular animal lectin as a glycan-binding receptors that recognize glycan epitopes on foreign pathogens and in the host systems.The present study reports a new type of serum lectin found in lamprey,Lampetra japonica.When proteinG agarose mixed with serum from lamprey was analyzed by SDS-PAGE,the lectin appeared as a single 35kD band.A 1005bp cDNA sequence obtained by RT-PCR from liver encoded a 335 amino acid secretory protein with homology to mammalian and aquatic organism intelectins.

关键词： Lamprey intelectin agglutination activity proteinG target immune defense

作者: Zhuang Xue FenFang Wu Yue Pang Rong Xiao Xin Liu Qing Wei Li

作者单位: Institute of Marine Genomics & Proteomics, Liaoning Normal University, Dalian 116029, China; School of life science, Liaoning Normal University, Dalian 116029, China

会议类型: 国内会议

会议名称: 2012遗传学进步促进粮食安全与人口健康高峰论坛

会议地点: 郑州

会议语种:英文

页码: 125-126

在线出版日期: 2012-08-13（万方平台首次上网日期，不代表论文的发表时间）