Studies on arterial AT1R, eNOS and vascular remodeling in salt-sensitive hypertensive rat by sensory nerve injury

摘要：

　　Objective To detect the expression of AT1R,eNOS of artery in mRNA and protein levels and the changes of vascular structure.To analyse the relationship among AT1R,eNOS and vascular remodeling,so as to explore the molecular mechanism of vascular remodeling in the salt-sensitive hypertension rats induced by sensory denervation,providing the theory basis for prevention and treatment in the salt sensitive hypertension.Method In this hypertension model,newborn male Wistar rats were given 50 mg/kg capsaicin subcutaneously on the 1 st and 2nd day.

关键词： Sensory Denervation Salt-Sensitive Hypertension AT1R eNOS Vascular remodeling

作者: BAI Bao-qin YANG Jian-yi LI Li ZHANG Juan WANG Wen-juan

作者单位: The cytology and genetics department.of Shanxi Medical University, Taiyuan,030001 ,P.R.China

会议类型: 国内会议

会议名称: 2012遗传学进步促进粮食安全与人口健康高峰论坛

会议地点: 郑州

会议语种:英文

页码: 127-128

在线出版日期: 2012-08-13（万方平台首次上网日期，不代表论文的发表时间）