Draft Genome Sequence ofStreptomyces sp.AA1529,Isolated from the Yellow Sea
Streptomyces,the largest genus of actinobacteria,is a remarkably rich source of natural products,accounting for production of over two-thirds of commercially available antibiotics today.This genus still produces a larger number and a wider variety of new antibiotics than members of any other genus.Here we report the draft genome sequence of a Streptomyces strain,AA1529,isolated from marine sediment of the Yellow Sea,which consists of 109 contigs totaling 7,285,977 bases with an average GC content of 72.8%,predicting 6,334 open reading frames,5 rRNA operons (16S-23S-5S),and 58 tRNA genes.Its genome encodes a subset of unique genes and gene clusters for diverse secondary metabolites,including a variety of terpenoids and polyketides,and provides a genetic basis for further investigation of this strain”s chemical biology,indicating great promise as a source for rational screening of novel bioactive compounds.
Streptomyces sp.AA1529 Draft Genome Sequence the Yellow Sea Natural product screening
Zhi-Qiang Xiong Yong Wang
Key Laboratory of Synthetic Biology,Institute of Plant Physiology and Ecology,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200032,China
国内会议
上海
英文
18-18
2012-08-01（万方平台首次上网日期，不代表论文的发表时间）