ATTRIBUTABLE CAUSES OF LUNG CANCER INCIDENCE AND MORTALITY IN CHINA

摘要：

　　Objective:This work aims to estimate the contribution of known risk factors of lung cancer in China and to provide evidence to support the National Cancer Prevention and Control Program in China.Methods:The proportion of lung cancer attributable to specific risk factors were calculated.Exposed data were from meta-analyses and large-scale national surveys of representative samples of Chinese population.Data on relative risks were from meta-analyses and large-scale prospective studies.Lung cancer mortality and incidence were originated from the 3rd national death cause survey and population-based cancer registries in China.Results:We estimated that 285,304 lung cancer deaths (men:229,990; women:55,314) and 327,465 cases (men:263,576,women:63,889) were attributable to smoking,involuntary smoking (women only),occupational agents,indoor radon,low fruit intake in China in 2005.About 75.04% of lung cancer deaths among men and 18.35% among women were attributable to tobacco smoking.About 10.63% of lung cancer deaths in men and 7.04% in women were caused by occupational agents,and 0.15% for both genders caused by indoor radon.Low fruit intake was responsible for 12.24% lung cancer deaths among men and that of 12.60% among women.The fraction of lung cancer deaths attributable to involuntary smoking from the spouse or at the workplace among non-smoking women was 11.10%.Conclusions:Smoking,occupational agents,indoor radon,and low fruit intake are responsible for 80% of lung cancer mortality and incidence among men and 41% among women (including involuntary smoking).However,more than half of lung cancer deaths and cases among women are caused by other risk factors.It is necessary to conduct large-scale,case series studies to demonstrate genetic factors and other important risk factors of lung cancer in women.

关键词： lung cancer population attributable fraction smoking passive smoking occupational agents indoor radon low fruit intake

作者: FAN Yaguang Paolo Boffetta WANG Jianbing JIANG Yong Li Ping XIAO Huijuan CHEN Wanqing WEI Wenqiang QIAO Youlin ZHOU Qinghua

作者单位: From Tianjin Lung Cancer Institute,Tianjin Medical University General Hospital Tianjin,300192 The Tish Cancer Institute,Mount Sinai School of Medicine,New York,NY,USA and International Preventio Department of Cancer Epidemiology and National Office for Cancer Prevention and Control Cancer Insti

会议类型: 国内会议

会议名称: 第十三届中国科协年会第18分会场——癌症流行趋势和防控策略研究研讨会

会议地点: 天津

会议语种:英文

页码: 237-237

在线出版日期: 2011-09-21（万方平台首次上网日期，不代表论文的发表时间）